August 27, 2014
Menopause and cardiovascular disease
Menopause and cardiovascular disease
Our expert is Virginia M. Miller, Ph.D., professor of physiology and surgery at the Mayo Clinic, where he is director of a specialized research on gender differences and Director of the Interdisciplinary Research Building career investigators Health Research Center women. The work of Dr. Miller examined how estrogen affects the progression of atherosclerosis and the changes in brain structure and cognition in menopause. If it explores a medical problem that you wish I can see here, let me know.
Best,
Mitzi Perdue
mperdue@liebertpub.com
MENOPAUSE has an impact on cardiovascular disease
Menopause with dramatic changes in the sex steroid estrogen, and these changes may accelerate the development of cardiovascular diseases. The women behind the men in the development of cardiovascular disease until menopause and the risk of developing cardiovascular disease increases about the same as for men.
Estrogen treatments are not all equal
There are advantages and disadvantages to the use of estrogen therapy for menopausal symptoms and one of the main issues associated to judge, both by scientists and doctors is that tendency all along estrogen treatments. Initiative for Women's Health, which showed negative for hormone replacement therapy, with conjugated equine estrogens (CEE) used for women without a uterus, in women with a uterus, estrogen cardiovascular was with a synthetic progestin used consequences. But other estrogen preparations such as transdermal estradiol and oral estrogen have different profiles and absolute risk.
Size does not fit all
It is important that the age and condition of the underlying health of women who take these products. Data from observations and epidemiological studies show initiative and the health of women who pay attention to the health status of women, if hormone replacement therapy is prescribed have. Those who are at low risk for cardiovascular disease may do well with hormone replacement therapy, in contrast to increased cardiovascular risk factors.
REQUIRED HRT O surgically induced premature menopause
Another argument in a size not for all women who either had an early menopause or surgical menopause. After studying Health Initiative of Women, it seemed that the HRT was bad for everyone, but in both cases, the benefits clearly outweigh the damage. Depriving women of HRT increases the risk of mortality. Women in both groups benefit if HRT had occurred until natural menopause.
Physicians should instruct additional investigations
The cardiovascular system of women is quite different than in humans, especially because of the need to adapt to the pregnancy. This leads to the hypothesis that treatment results are not the same for women as for men. Although the differences in the response to various treatments few published studies, more women required in clinical trials, and the analysis of data from clinical trials should be carried out with sex. Guidelines for treatments are effective for women, more data are needed to provide useful information for clinical use in their practice. We need a wave of doctors who order these studies.