Sarah Knapton
Published 08/18/2014 | 12:00
A pill for hair loss hair completely renovated three patients as a breakthrough by scientists as "dramatic" and healing seems "exciting".
Doctors a pilot After identification of the immune cells for destruction of hair follicles are responsible for the condition in the.
Within four to five months after the given to the drug, three patients completed Ruxolitinib hair growth.
"We have just begun testing the drug in patients, but if the drug continues to be safe and successful, there is a significant positive impact on the lives of people with this disease have," said Dr. Raphael Clynes, Columbia University Medical Center in new York.
However, the team said more evidence is needed before the drug can be safely used for the treatment of hair loss.
Alopecia is a common autoimmune disease that can lead to total hair loss.
Joanna Rowsell, the pilot of the Olympic Gold medal, has suffered from the disease for 13 years. The 23-year-old took his helmet during the 2012 Games in London to show that they are almost completely bald and took her medal before an audience of 17 million people, without his wig usual.
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There is no relationship between hair loss and hair loss, hair loss, hormonal mechanical 6.5 million people in the UK affected.
The study followed tests in mice with two new drugs, the so-called JAK inhibitors that can be taken in the form of tablets and is used to block the immune system.
Ruxolitinib is approved for the treatment of cancer of the bone marrow in America and Europe. Another drug, tofacitinib is approved for the treatment of rheumatoid arthritis in the United States in Europe, but not.
In experiments with mice, both drugs completely restored the hair of animals with hair loss at 12 weeks.
Patients in the study had moderate to severe alopecia areata, the hair loss caused irregular head. Gail Porter is a severe form of the disease called alopecia totalis, which affected in complete baldness results.
Each patient received 20 mg twice daily Ruxolitinib. Drug efficacy is related to the disappearance of the immune cells attack the hair follicles.
"We still have more tests to determine the Ruxolitinib be used in alopecia areata, but this is good news," said Dr. Clynes.
The research appears in the latest online issue of the journal Nature Medicine.
Irish Independent